Principal Investigator (PI): Orly Vardeny

PI Department: UW School of Pharmacy

Project Study Title: Angiotensin Converting Enzyme I/D Polymorphism in Hispanic Patients with Type 2 Diabetes and Its Relationship with Microalbuminuria

Summary of Study: The purpose of this study is to understand how certain genes affect the risk of kidney damage and kidney disease from diabetes and if individuals who are of Hispanic/Latino origin have these genes more or less often than white people not of Hispanic/Latino descent.

Objective: This study wants to find out if people of Hispanic/Latino origin are more likely to have a certain gene that can increase the risk of kidney damage from diabetes than white individuals who are not of Hispanic/Latino descent. Identifying a gene that increases risk of kidney damage may lead to better treatment of individuals at higher risk in the future.

DFM Clinic(s): Wingra Family Practice, UW Health Sun Prairie

DFM Faculty Contact: Connie Kraus

Study Contact Person:
Orly Vardeny
(609)265-0591
ovardeny@pharmacy.wisc.edu

Date of Approval: January, 2006

Dates of Study: Ongoing

Study Implications: About 50 people (25 subjects of Hispanic/Latino origin and 25 white subjects not of Hispanic/Latino origin) who have had a urine test showing the presence of small amounts of protein (microalbuminuria) will be asked to give a blood sample.