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Innate Immunity and RSV Infection in Children

Principal Investigator (PI): Theresa Gilbert, MD

PI Department: Pediatrics

Project Study Title: Innate Immunity and RSV Infection in Children

Summary of Study: The purpose of this study is to identify factors that may affect how the immune system responds to a common virus, called respiratory synctial virus (RSV).

Objective: Do children with parental history of asthma that carry a certain gene have a less severe iflammatory response during an RSV infection thatn similar children with other genotypes? This is a prospective, longitudional, case-control study.

Study Design: Enrolled Chilren/families will provide consecutive and separate illness nasal washes ( at least one per week) until the nasal sample becomes RSV positive. Once the nasal sample is positive for RSV, the second study visit with a blood draw collection will be scheduled 4-8 weeks later.

DFM Clinic(s): Wingra Family Practice, UW Health Sun Prairie; follow up at UW Hospital, UW Affiliated

DFM Faculty Contact: Mary Beth Plane

Study Contact Person:
Theresa Guilbert, MD
Associate Professor of Pediatrics
608.263.9608
tguilbert@pediatrics.wisc.edu

Date of Approval: January, 2008

Dates of Study: Ongoing