- Our Department
- Residency Programs
- Med Student Education
- Research
- Externally Funded Research
- Alcohol Biomarkers in Gen Clinical Settings
- Automated Clinician Reminder System
- College Health Intervention Projects (CHIPs)
- Communities at Risk
- Echinacea Cold Study
- Healthy Children, Strong Families (HCSF)
- Healthy Choices
- Healthy Moms
- Magnetic Resonance Imaging in a Study of Prolotherapy
- Mindfulness Meditation for Alcohol Relapse Prevention
- Obesity, Aging and Cancer Cost
- Proactive Risk Assessment of Primary Care of the Elderly
- Problem Density Mental Workload
- Prolotherapy for Osteoarthritic Knee Pain
- SIMmersion
- STAR-SI
- Time to Event Analysis of Drug Court Health Outcomes
- Topical Honey for Diabetic Foot Ulcers
- Treatment of Children with ADHD and FASD
- Wisconsin Nutrition & Growth Study (WINGS)
- WURSS
- DFM-Funded Projects
- Past Projects
- Publications
- Study Recruitment
- Research Approved for DFM Clinics
- Wisconsin Research & Education Network (WREN)
- Externally Funded Research
- Patient Care
- Fellowships
- Innovation & Outreach
- PA Program
Prolotherapy for Osteoarthritic Knee Pain
Key DFM Personnel
David Rabago, MD - Principal Investigator
Jeffrey Patterson, DO Prolotherapist
Jessica Grettie, Research Specialist, is the Study Coordinator
Study Contact Phone: 608-576-2738
The Study is being conducted with the UW Divisions of Sports and Rehabilitation Medicine
Participating Physicians
David Bernhardt, MD
Kathleen Carr, MD
Jerome Ebert, MD
Greg Landry, MD
James Leonard, MD
Funding Source
National Institute of HealthBackground
Prolotherapy is a treatment of Dextrose (sugar-water) injections in and around the knee. They are designed to stimulate the body's own healing process to strengthen the structures of the knee, improving mobility, and decreasing pain.
Prolotherapy has been used for over 100 years. Current evidence suggests that Prolotherapy may be effective in reducing the pain of knee arthritis, a degenerative condition causing the components of the knee to wear down. But conclusive evidence is lacking. This study will test whether Prolotherapy is effective for relief of arthritic knee pain. Experience at the University of Wisconsin suggests that Prolotherapy is equal to or better than physical therapy for arthritic knee pain.
Methods
Adults 40-70 years old who have had arthritic knee pain for 3 to 10 years are randomized one of three groups, complete six sets of questionnaires about their knee pain over the course of one year and may have three knee treatments.