Current WREN Research Projects

Principal Investigator:  Annette Totten, PhD – Oregon Health & Science University

Project Summary:  This project is designed to address the PCORI-identified need “for evidence to support adults with advanced illnesses and their caregivers in care planning over time so that care is consistent with their goals and preferences”.  This will be a cluster-randomized trial comparing team-based versus primary care clinician-focused advance care planning in practice-based research networks.

Funding Agency:  Patient-Centered Outcomes Research Institute (PCORI)

PI(s): Sarina Schrager, MD, MS; Makeba Williams, MD, NCMP, FACOG; Mary Henningfield, PhD; Earlise Ward, PhD

Funding Agency: UW Madison Department of Family Medicine & Community Health

What problem is this study trying to solve?
African American women have more severe vasomotor symptoms, experience symptoms for longer durations than white women, and have more interrupted sleep. African American women also describe not being heard by members of the health care system. Thus, the menopausal care needs of African American women are doubly underserved.

What will be studied?
This project aims to explore African American women’s experiences with menopause and with the health care system. We will conduct focus groups and interviews with African American women to obtain a rich dataset of experiences to ensure that the perspectives of African American women are adequately heard.

What could the study mean for clinicians and patients?
This study will provide information that can help primary care clinicians better understand and treat African American women for their menopause symptoms.

Principal Investigator:  Eric Simpson, MD, MCR – Oregon Health & Science University

Project Summary:  This is a pragmatic, multi-site, randomized community-based trial in which dyads of a parent or legal guardian (“parent”) and an infant age 0 to 2 months are enrolled to test the hypothesis that a skin care regimen utilizing emollient therapy from birth can prevent or delay onset of atopic dermatitis.

Funding Agency: National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIH-NIAMS)

Principal Investigator: David Feldstein, MD UW SMPH – Department of General Internal Medicine

Project Summary: The overall objectives are to 1) implement registered nurse (RN)-driven clinical decision support (CDS)containing integrated clinical prediction rules (iCPRs) [decision aids embedded into the electronic health record which determine risk of bacterial infection based on elements of the patient history and physical examination] and 2) determine the impact of RN-driven CDS on inappropriate antibiotic prescribing and resource use.

Funding Agency: New York University School of Medicine

Principal Investigator(s):  Jennifer Weiss, MD, MS – UW Madison School of Medicine &n Public Health

Project Summary:  The overall objective of this project is to examine and characterize the system and clinic factors that distinguish high- from lower-performing rural clinics and identify successful CRC screening strategies in high-performing clinics, including strategies that are successful for subgroups with disproportionately low CRC screening (Medicaid, racial/ethnic minorities).

Funding Agency:  American Cancer Society

Principal Investigator(s):  Sarina Schrager, UW Madison Department of Family Medicine & Community Health; Amye Tevaarwerk, UW Madison School of Medicine & Public Health

Project Summary:  In order to improve breast cancer screening rates and survivorship in Prairie Ridge Health’s (PRH’s) rural service area, the reasons why residents are not obtaining mammography must be identified, understood and addressed. A more in depth evaluation is needed to develop a comprehensive plan to address the array of limitations specific to PRH’s rural location (biology, individual characteristics, social and physical contexts, and political/economic environment).

Funding Agency:  UW Madison Carbone Cancer Center

Principal Investigator(s):  Yao Liu, MD, MS – UW Madison School of Medicine & Public Health Department of Ophthalmology & Visual Services

Project Summary:  Teleophthalmology is a validated method for diabetic eye screening that is underutilized in U.S. primary care clinics. Even when made available to patients, its long-term effectiveness for increasing screening rates is often limited.  This project will be working with 15-20 primary care clinics nationwide to test the Teleophthalmology Implementation Program in a 5-year randomized controlled trial.

Funding Agency:  National Institutes of Health/National Eye Institute

Principal Investigator:  Corrine Voils, PhD – UW SMPH, Dept of General Surgery

Project Summary:  This study will provide critical insight into the efficacy of systematically involving domestic partners to optimize long-term weight loss. Results from the mediation analyses will provide unique knowledge about the mechanisms underlying a couples’-based approach for patient weight management. As such, the results will inform future intervention refinements to optimize patient outcomes and scalability. Completion of this study will contribute to our long-term goal of identifying and implementing efficacious, cost-effective approaches to reduce obesity and associated outcomes.

Funding Agency:  National Institutes of Health (R01)

Principal Investigator: Bruce Barrett, MD, PhD, UW SMPH – Department of Family Medicine and Community Health

Project Summary:  A Comparative Effectiveness Randomized Controlled Trial of Mindfulness Meditation versus Cognitive Behavioral Therapy for Opioid-Treated Chronic Low Back Pain

This randomized, controlled trial will test the relative benefit of Mindfulness Meditation (MM) vs. Cognitive Behavioral Therapy (CBT) in improving outcomes for patients with chronic low-back pain treated with opioids.

Funding Agency:  Patient-Centered Outcomes Research Institute (PCORI)

Meta-Network Affiliations

Project Summary: Creation of research and learning consortium of 6 PBRNs: Oregon, Colorado, Wisconsin, Iowa, and Quebec to accelerate the conduct of PBRN research through a common infrastructure enabling the efficient conduct of research. The consortium will promote continuous learning across networks and practices for evidence dissemination and knowledge transfer.

Funding Agency: Agency for Healthcare Research and Quality

Workshop: Multi-Network Research Collaboration: Steps to Success

Wisconsin Research & Education Network (WREN)

Just Published!

The Burden of Childhood Atopic Dermatitis in the Primary Care Setting:  A Report from the Meta-LARC Consortium

This article is a result of Eric Simpson’s pilot study, Community-based Assessment of Skin Care, Allergies and Eczema (CASCADE).

Identification of Barriers, Facilitators and System-Based Implementation Strategies to Increase Teleophthalmology Use for Diabetic Eye Screening in a Rural US Primary Care Clinic: A Qualitative Study

This article captures the real-world perspectives of patients and providers in using teleophthalmology to address diabetic eye screening. Dr. Liu’s NIH-funded study is one of the first to address implementation strategies suggested by both patients and primary care providers.

Congratulations Authors!